Cart 0

Amytracker™

Amytracker™ are optotracers that detect amyloids and other protein aggregates

Amytracker™ allow you to visualize amyloids directly, without using antibodies or any toxic reagents. We developed Amytracker™ to stain amyloid fibrils, and even pre-fibrillar species in tissue sections and working to expand the range of applications. We provide Amytracker™ in a range of different colors to make your amyloid staingings shine!

Check out our range of
Amytracker™ products!

Staining with Amytracker™ is powerful, fast and simple

  • Simple
    Stain and go. No need for complex protocols, additional reagents or secondary antibodies.
  • Fast
    Amytracker™ help to minimize your assay time.
  • Stable
    Amytracker™ are thermo- and photo-stable. We recommend storage in the frige, but you can do your assay on the bench at any temperature you like.
  • Sensitive
    Amytracker™ are more sensitive than conventional Amyloid stains.
  • Non-toxic
    Safe to use for you and your experiments.
  • Versatile
    Amytracker™ come in a range of colours. They work with your existing microscope setup.

Amytracker™ for a variety of applications

Our aim is to provide you with Amytracker™ for a variety of applications. We work closely with our partners at research institutions to test our products in the real-life research environment. Our Amytracker™ have been used to stain extracellular amyloid deposits, intracellular inclusion bodies and even aggregates of prion proteins in various species and tissues. With Amytracker™ you will be able to detect early as well as mature plaques. That means you can detect prefirillar species, which cannot be picked-up with the common amyloid dyes. You can detect fully formed protein aggregates with superior intensity. Check out our Science Room for more information.

Inclusion bodies in muscle fibres observed in systemic inclusion body myositis using Amytracker™545 (Klingstedt et al. (2013) Chembiochem 14(5):607-16). Image courtesy of Therese Klingstedt.

Extracellular amyloid β deposits as seen in systemic amyloidosis tissue when staining with Amytracker™545 (Sjölander et al. (2016) Amyloid 23(2):98-108). Image courtesy of Daniel Sjölander.

Intracerebral amyoid in brain sections of transgenic APP/PS1 mice. Acquired using Spectral imaging with our yellow Amytracker™545 (Nyström et al. (2013) ACS Chem Biol 8:1128-1133). Image courtesy of Sofie Nyström.

Our blue Amytracker™480 bound to Aβ deposits in the vasculature and to core plaques as well as neurofibrillary tangles in the brain parenchyma (Shirani et al. (2015) Chem Eur J 21:15133-15137). Image courtesy of Hamid Shirani.

Our red Amytracker™680 bound to Aβ deposits in the vasculature and to core plaques as well as neurofibrillary tangles in the brain parenchyma (Shirani et al. (2015) Chem Eur J 21:15133-15137). Image courtesy of Hamid Shirani.

Human AD brain sections stained with our green Amytracker™515 Intracerebral amyoid in brain sections of transgenic APP/PS1 mice (Åslund et al. (2009) ASC Chem Biol 4(8):673-684). Image courtesy of Andreas Åslund.

Aggregated Insulin fibrils stained Amytracker™545 and excited at 405 nm. The Image was acquired with a spectral imaging system. Image courtesy of Ferdinand X. Choong.

A fat biopsy stained with Amytracker™545 (Sjölander et al. (2016) Amyloid 23(2):98-108). Image courtesy of Daniel Sjölander.

Terms & Conditions

For detailed information on Terms & Conditions, please click the link below.

Terms & Conditions

Support

If you have any questions related to shipping, ordering, price or about our products, please do not hesitate to contact us.

info@ebbabiotech.com