Amyloid detection has been notoriously difficult since current methods are either laborious, toxic and/or tend to detect mature fibrils but not protofibrils or premature aggregates.
Amytracker are fluorescent tracer molecules binding to amyloids with high sensitivity. Amytracker have been shown to bind to prefibrillar states of amyloids and might therefore help to detect and investigate earlier pre-pathological states of amyloid diseases. As Amytracker are fluorescent only when bound to their target, they are well suited for fibrillation studies with much shorter lag phase and less background compared to other small molecule ligands. Amytracker are non-toxic and are well suited for life-cell applications crossing cell membranes with minimal incubation times.
Amytracker staining is simple, fast and non-toxic!
||Fast: Amytracker help to minimize your assay time.|
|Simple: Stain and go. No need for complex protocols, additional reagents or secondary antibodies.|
|Stable: Amytracker are thermo- and photo-stable. We recommend storage in the fridge, but you can do your assay on the bench at any temperature you like.|
|Non-toxic: Safe to use for you and your experiments.|
|Accurate: Amytracker are more sensitive than conventional Amyloid stains. Amytracker molecules come in a range of colours. They work with your existing microscope setup.|