Amytracker - Publications
Amyloids trigger proinflammatory signalling Mul...
β-2-microglobulin is a protein present in all nucleated cells and is elevated in many tumors or inflammatory diseases. It is well known that the protein has a propensity for aggregation....
Amyloids trigger proinflammatory signalling Mul...
β-2-microglobulin is a protein present in all nucleated cells and is elevated in many tumors or inflammatory diseases. It is well known that the protein has a propensity for aggregation....
Amytracker: a tool to identify toxic dipeptide ...
Repetitive genomic regions are known to expand across generations, due to errors during their replication, and cause a series of - mainly - neurological diseases collectively called repeat expansion diseases....
Amytracker: a tool to identify toxic dipeptide ...
Repetitive genomic regions are known to expand across generations, due to errors during their replication, and cause a series of - mainly - neurological diseases collectively called repeat expansion diseases....
How mutations contribute to pathological divers...
How can a single protein be responsible for a variety of diseases? Synucleinopathies are clinically and pathologically heterogeneous disorders that are caused by conversion of α-synuclein to pathologic oligomers and...
How mutations contribute to pathological divers...
How can a single protein be responsible for a variety of diseases? Synucleinopathies are clinically and pathologically heterogeneous disorders that are caused by conversion of α-synuclein to pathologic oligomers and...
Deciphering the complexity of intracellular Tau...
Tau is an intrinsically disordered protein with the key function to stabilise axonal microtubules. In several neurological disorders collectively known as Tauopathies, tau proteins form aggregates that accumulate in cells...
Deciphering the complexity of intracellular Tau...
Tau is an intrinsically disordered protein with the key function to stabilise axonal microtubules. In several neurological disorders collectively known as Tauopathies, tau proteins form aggregates that accumulate in cells...
Linking aggregate size and toxicity using Amytr...
In the context of neurodegenerative diseases, large, fibrillar amyloid deposits - such as Lewy bodies, Amyloid plaques, and Neurofibrillary tangles - characterize the pathology of the disease but it has...
Linking aggregate size and toxicity using Amytr...
In the context of neurodegenerative diseases, large, fibrillar amyloid deposits - such as Lewy bodies, Amyloid plaques, and Neurofibrillary tangles - characterize the pathology of the disease but it has...
Protein aggregation in wound healing
Lipopolysaccharide (LPS) is a cell envelope glycolipid produced by most gram-negative bacteria. When LPS is recognized by Toll-like receptor 4 (TLR4) an innate host-response to bacterial infection is triggered. To...
Protein aggregation in wound healing
Lipopolysaccharide (LPS) is a cell envelope glycolipid produced by most gram-negative bacteria. When LPS is recognized by Toll-like receptor 4 (TLR4) an innate host-response to bacterial infection is triggered. To...