Amytracker - Publications
Phase separated α-synuclein is more prone to ag...
Alpha-synuclein (α-Syn) aggregation hallmarks a group of neurodegenerative diseases known as synucleinopathies with Parkinson’s disease as its most well-known representative. The molecular mechanism behind the aggregation of α-Syn is still...
Phase separated α-synuclein is more prone to ag...
Alpha-synuclein (α-Syn) aggregation hallmarks a group of neurodegenerative diseases known as synucleinopathies with Parkinson’s disease as its most well-known representative. The molecular mechanism behind the aggregation of α-Syn is still...
FL-OPTIR for studying biophysical properties of...
Infrared (IR) spectroscopy is an invaluable tool to study the biophysical properties of amyloid aggregates. Although historically used as a tool for composition analysis of chemical compounds as it measures...
FL-OPTIR for studying biophysical properties of...
Infrared (IR) spectroscopy is an invaluable tool to study the biophysical properties of amyloid aggregates. Although historically used as a tool for composition analysis of chemical compounds as it measures...
Spatial pattern of microglial activation in rel...
Microglia cells play a vital role in regulating brain development, maintenance of neuronal networks, and injury repair. Their involvement in the progression of protein aggregation leading to neurodegenerative diseases is...
Spatial pattern of microglial activation in rel...
Microglia cells play a vital role in regulating brain development, maintenance of neuronal networks, and injury repair. Their involvement in the progression of protein aggregation leading to neurodegenerative diseases is...
Amyloidogenicity of SARS-CoV-2 spike protein
Amytracker 680 confirms the amyloid structure of spike protein aggregates Petrlova, J et al. (2022) SARS-CoV-2 spike protein aggregation is triggered by bacterial lipopolysaccharide. FEBS Lett. 596(19):2566-2575
Amyloidogenicity of SARS-CoV-2 spike protein
Amytracker 680 confirms the amyloid structure of spike protein aggregates Petrlova, J et al. (2022) SARS-CoV-2 spike protein aggregation is triggered by bacterial lipopolysaccharide. FEBS Lett. 596(19):2566-2575
Lewy body formation in seeding based neuronal m...
Amytracker 680 confirms amyloid structure in seeded α-synuclein aggregates rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proceedings of the National Academy of Sciences of...
Lewy body formation in seeding based neuronal m...
Amytracker 680 confirms amyloid structure in seeded α-synuclein aggregates rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proceedings of the National Academy of Sciences of...
Prolonged stress leads to accumulation of misfo...
Amytracker has been used to label amyloids in the nucleolus after exposure to prolonged stress Frottin, F et al. (2019) The Nucleolus Functions as a Phase-Separated Protein Quality Control Compartment. Science...
Prolonged stress leads to accumulation of misfo...
Amytracker has been used to label amyloids in the nucleolus after exposure to prolonged stress Frottin, F et al. (2019) The Nucleolus Functions as a Phase-Separated Protein Quality Control Compartment. Science...