Amytracker - Publications

Oxidative stress and amyloid formation contributes to phenylketonuria disease

Oxidative stress and amyloid formation contribu...

Phenylketonuria is an inherited disorder characterised by the inability to break down the amino acid L-phenylalanine (L-Phe). The disease is primarily caused by mutations in the gene that encodes phenylalanine...

Oxidative stress and amyloid formation contribu...

Phenylketonuria is an inherited disorder characterised by the inability to break down the amino acid L-phenylalanine (L-Phe). The disease is primarily caused by mutations in the gene that encodes phenylalanine...

The structural basis of TDP-43 aggregation

The structural basis of TDP-43 aggregation

More than 97% of sporadic and familial ALS involve the formation of cytoplasmic aggregates of TDP-43 (TAR DNA/RNA-binding protein 43). In their recent publication on Communication Biology, Akira Kitamura and...

The structural basis of TDP-43 aggregation

More than 97% of sporadic and familial ALS involve the formation of cytoplasmic aggregates of TDP-43 (TAR DNA/RNA-binding protein 43). In their recent publication on Communication Biology, Akira Kitamura and...

Uncovering a new link to amyloid formation in neurodegenerative diseases

Uncovering a new link to amyloid formation in n...

The 14-3-3 proteins regulate various cellular functions, including enzymatic activity and protein stability. The 14-3-3ζ isoform has been linked to neurodegenerative diseases due to its interaction with proteins like tau...

Uncovering a new link to amyloid formation in n...

The 14-3-3 proteins regulate various cellular functions, including enzymatic activity and protein stability. The 14-3-3ζ isoform has been linked to neurodegenerative diseases due to its interaction with proteins like tau...

Modular protein hydrogels for flexible applications

Modular protein hydrogels for flexible applicat...

Tissue models depend on 3D scaffolds to provide appropriate growth environments. Such scaffolds can be made from proteins forming amyloid fibrils. Amytracker has been shown to be an excellent tool...

Modular protein hydrogels for flexible applicat...

Tissue models depend on 3D scaffolds to provide appropriate growth environments. Such scaffolds can be made from proteins forming amyloid fibrils. Amytracker has been shown to be an excellent tool...

Amyloid formation in ALS: Redefining the role of TDP-43 inclusions

Amyloid formation in ALS: Redefining the role o...

Researchers from the University of Florence investigated the nature of TAR DNA-binding protein 43 (TDP-43) cytoplasmic inclusions, which are key pathological markers in neurodegenerative diseases like amyotrophic lateral sclerosis (ALS)...

Amyloid formation in ALS: Redefining the role o...

Researchers from the University of Florence investigated the nature of TAR DNA-binding protein 43 (TDP-43) cytoplasmic inclusions, which are key pathological markers in neurodegenerative diseases like amyotrophic lateral sclerosis (ALS)...

Amytracker confirms amyloid nature of inclusion bodies in muscle linked to gene mutations

Amytracker confirms amyloid nature of inclusion...

Distal myopathies are genetically heterogeneous diseases that primarily affect skeletal muscles, particularly in the hands and feet, although they can progress to other muscles. Previous research has identified more than...

Amytracker confirms amyloid nature of inclusion...

Distal myopathies are genetically heterogeneous diseases that primarily affect skeletal muscles, particularly in the hands and feet, although they can progress to other muscles. Previous research has identified more than...