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Optotracers - multifunctional fluorescent tracers

On the first of June 2021, Ferdinand Choong, Ebba Biotech's co-founder, and Assistant Professor at Karolinska Institutet and AIMES (Center for the Advancement of Integrated Medical and Engineering), presented his research using Ebba Biotech's optotracers at the digital event Lab & Diagnostics of the Future 2021, held by Life Science Sweden.

At this event, Ferdinand spoke about Ebba Biotech's optotracers multifunctional tracer for disease research and diagnostics. He explains the technical concept in large and Ebba Biotech's three product series,

Amytracker - used to detect amyloids and other protein aggregates,
Ebba Biolight - used to detect bacteria and biofilm,
Carbotrace - used for mapping composition of biobased material.

At AIMES, Ferdinand is applying optotracing to improve research and diagnostics of infection, where bacterial infection has a significant role, and biofilm might be the key reason why bacterial infection exists, which he describes in more detail.




Carbotrace 540 helps to determine purity of plant raw materials

Researchers from the Royal Institute of Technology and Karolinska Institutet in Sweden reported about an environmentally friendly process to obtain pure cellulose nanofibrils from the green macroalgae ulva lactuca (Wahlström et al. (2020) Cellulose 27, 3707–3725). Analysis of the monosugars revealed that the extracted cellulose contains mainly glucose, but also a fraction of xylose. Carbotrace 540 allowed the researchers to analyze the carbohydrates in its polymeric state and was key to uncover that the macroalgae contain a mixture between highly pure and a xylose-glucose polysaccharide, such as xyloglucan.

The video clip shows the eco-friendly extraction of of pure cellulose from green macroalgae from the Swedish west coast.



Carbotrace-like molecules for visualization of cellulose in plants

A research paper (Choong et al. (2018) Scientific Reports, 8, 3108) uses a Carbotrace-like molecule to visualize the location and structure of cellulose in plant cells.

The video below explains why it is so difficult to switch to plants for producing renewable resources and how Carbotrace can help in the process.



Carbotrace supports circular economy

In a research paper published in Cellulose (Choong et al. (2019) Cellulose, 26, 4253–4264), our structure-responsive optotracer molecule Carbotrace 680 was used to demonstrate the potential of optotracing for carbohydrate anatomical mapping and spectral imaging.

The video clip below illustrates why our current model of Take, Make, Dispose is draining our planet of natural resources and why circular economy and renewable resources are the answer. Learn how Carbotrace can help to identify renewable resources in plant biomass and support circular economy in the food & beverage, pharmaceutical and chemical industry.