Adam Kreutzer about Amytracker 680:
“I have been very happy with the Amytracker dyes I have used thus far. I have easily worked the Amytracker dyes into my free-floating, fixed brain tissue immunostaining workflow. The nice thing about the Amytracker dyes is that I don’t have to dehydrate the tissue in a series of ethanols and xylene, which is required for the widely used thioflavin and congo red dyes. The Amytracker dyes can just be applied to the tissue in TBS and then imaged. I often don’t even wash the tissues after treatment with the Amytracker dyes."
Adam Kreutzer, PhD, Associate Project Scientist at the Department of Chemistry, Nowick Laboratory, University of California, Irvine, USA
Keiza Jack about Amytracker 540:
“I have used Amytracker 540 in my PhD project as a tool to measure the structural differences of prion structures and prion-seeded amyloid fibrils. Amytracker 540 reports sensitively on subtle structural differences between protein structures, giving me a fast and reproduceable method to compare protein structures, which was essential to investigate my thesis"
Kezia Jack from MRC Prion Unit, Institute of Prion Diseases, University College London, London, UK
Dr. Jaakko Sarparanta about Amytracker 680:
”We used Amytracker 680 to study the amyloid-like nature of pathological protein aggregates in muscle sections. The bright positive staining was easily interpreted and provided the much needed support for our Congo Red results.”
Dr. Jaakko Sarparanta, Folkhälsan Research Center, Helsinki, Finland.
M. Garcia about Amytracker 520:
"We are studying Alzheimer’s disease in mouse models and use a variety of anti-amyloid-beta antibodies and traditional dyes to look at amyloid-beta aggregation. Amytracker 520 gave a very clean staining with high signal to noise. It was easy to use as a part of routine immunohistochemistry and made for a great complement to Thioflavin S staining to detect dense-core plaques with much less background."
M. Garcia (MSc), Doctoral student, Sweden