Amytracker - Publications

When Amyloids Meet Viruses: α-Synuclein Fibrils Enhance HIV-1 Infection

When Amyloids Meet Viruses: α-Synuclein Fibrils...

HIV-associated neurocognitive disorders are observed in 30-50% of infected individuals, but they are poorly understood. A recent study published in Nature Communications uncovers a striking interaction between neurodegenerative disease-associated amyloids...

When Amyloids Meet Viruses: α-Synuclein Fibrils...

HIV-associated neurocognitive disorders are observed in 30-50% of infected individuals, but they are poorly understood. A recent study published in Nature Communications uncovers a striking interaction between neurodegenerative disease-associated amyloids...

Antibodies Against a Synthetic Aβ Trimer-Mimic to Map Amyloid Pathology

Antibodies Against a Synthetic Aβ Trimer-Mimic ...

Understanding how amyloid-beta (Aβ) aggregates in Alzheimer’s disease (AD) is crucial for advancing diagnostics and treatment. Adam Kreutzer and their colleagues at the University of California Irvine developed a structurally...

Antibodies Against a Synthetic Aβ Trimer-Mimic ...

Understanding how amyloid-beta (Aβ) aggregates in Alzheimer’s disease (AD) is crucial for advancing diagnostics and treatment. Adam Kreutzer and their colleagues at the University of California Irvine developed a structurally...

Unraveling Tau Propagation: Amytracker Reveals ...

Video: Astrocyte-to-astrocyte transfer of AD tau fibrils through tunneling nanotubes (TNTs). Time-lapse microscopy of Amytracker-labelled AD tau fibrils (shown in red) demonstrating direct cell-to-cell transmission between human astrocytes. Video from...

Unraveling Tau Propagation: Amytracker Reveals ...

Video: Astrocyte-to-astrocyte transfer of AD tau fibrils through tunneling nanotubes (TNTs). Time-lapse microscopy of Amytracker-labelled AD tau fibrils (shown in red) demonstrating direct cell-to-cell transmission between human astrocytes. Video from...

Copper’s role in prion protein misbehaviour

Copper’s role in prion protein misbehaviour

Prion diseases are fatal neurodegenerative disorders caused by the misfolding and aggregation of prion proteins (PrP). Although copper (Cu2+) imbalance has long been suspected to play a role in these...

Copper’s role in prion protein misbehaviour

Prion diseases are fatal neurodegenerative disorders caused by the misfolding and aggregation of prion proteins (PrP). Although copper (Cu2+) imbalance has long been suspected to play a role in these...

How functional amyloids help regulate stress responses

How functional amyloids help regulate stress re...

Protein aggregation is traditionally seen as a pathological process, hallmark of neurodegenerative diseases and systemic amyloidoses. However, emerging evidence reveals that amyloid aggregation is not merely the consequence of protein...

How functional amyloids help regulate stress re...

Protein aggregation is traditionally seen as a pathological process, hallmark of neurodegenerative diseases and systemic amyloidoses. However, emerging evidence reveals that amyloid aggregation is not merely the consequence of protein...

Amytracker aids in designing small molecules to inhibit aggregation of α-synuclein

Amytracker aids in designing small molecules to...

Small molecules with the ability to inhibit the nucleation process and stop the aggregation of α-synuclein have immense potential to help people suffering from Parkinson's. Availability of several aSyn protein...

Amytracker aids in designing small molecules to...

Small molecules with the ability to inhibit the nucleation process and stop the aggregation of α-synuclein have immense potential to help people suffering from Parkinson's. Availability of several aSyn protein...