Amytracker 540 is our yellow fluorescent optotracer molecule for labeling protein aggregates with repetitive arrangement of β-sheets. It labels Aβ plaques and neurofibrillary tangles in tissue sections with AD pathology and α-synuclein aggregates in tissue sections with PD pathology.
As all our optotracers, Amytracker 540 is exceptionally photostable and fluorogenic. When bound to a target, Amytracker 520 can be imaged using fluorescence microscopy and spectral information can be acquired using a fluorescence spectrophotometer. Use recommended filter sets as well as excitation- and emission wavelengths according to Table 1.
|Amytracker 540||480 nm||540 nm||FITC, GFP, YFP|
Amytracker 540 is available as a 1 mg/ml solution in volumes ranging from 10 - 200 µL (see volumes and prices in the list below). As our standard solvent, we use ultrapure water. Please contact us for custom options.
DISCLAIMER: Amytracker are exceptionally stable and there is no direct requirement of handling or storing them in the dark or refrigerated. However, evaporation of aqueous solvent can occur upon opening/handling. Please make sure to close the container carefully, spin down liquid and use up small volumes quickly.
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