How to reference Amytracker

Amytracker are fluorogenic molecules that fluoresce upon binding to protein aggregates. Building on the broader field of amyloid-sensitive luminescent conjugated oligothiophenes (LCOs), Amytracker are structurally distinct LCO-related molecules. All Amytracker variants are designed to bind to the Congo red binding pocket on the amyloid fibril. A minimum of eight in-register parallel-β-strands are required for binding. As Amytracker are structural markers, you can achieve reliable fluorescent labeling of amyloids derived from a variety of amyloidogenic proteins or peptides from different species.