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Superresolution microscopy

Superresolution microscopy

Super-resolution microscopy is becoming an important tool to study biological structures. As super-resolution techniques like STED overcome the physical diffraction limit of light, new microscopes with ever-decreasing resolution limits are being developed. Using these exciting techniques, the constraints are now imposed by the probes used for labelling. With STED microscopy, reaching a resolution of 20–40 nm, antibodies are no longer suitable as labelling probes sinceconjugated fluorophores will seem to be...
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In vivo amyloid staining

In vivo amyloid staining

Intravital imaging is allowing researchers to capture images of biological processes in live animals. It has become an advanced tool to study the progression of Alzheimer's disease in transgenic mice. In vivo imaging using two-photon microscopy is an advantageous technique for observing tissues and organs at high resolution. Amytrackerâ„¢ are suitable for in vivo studies since our probes are non-toxic, cross the blood-brain barrier and stain fibrous deposits in animal...
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