Amyloid detection has been notoriously difficult since current methods are either laborious, toxic and/or tend to detect mature fibrils but not protofibrils or premature aggregates. Amytracker™ are fluorescent tracer molecules binding to amyloids with high sensitivity. Amytracker™ have been shown to bind to prefibrillar states of amyloids and might therefore help to detect and investigate earlier prepathological states of amyloid diseases. As Amytracker™ are fluorescent only when bound to their target, they are well suited for fibrillation studies with much shorter lag phase and less background compared to other small molecule ligands. Amytracker™ are non-toxic and are well suited for life-cell applications crossing cell membranes with minimal incubation times.
Amytracker staining is simple, fast and non-toxic!
Simple Stain and go. No need for complex protocols, additional reagents or secondary antibodies.
Fast Amytracker™ help to minimize your assay time.
Stable Amytracker™ are thermo- and photo-stable. We recommend storage in the frige, but you can do your assay on the bench at any temperature you like.
Sensitive Amytracker™ are more sensitive than conventional Amyloid stains.
Non-toxic Safe to use for you and your experiments.
Versatile Amytracker™ come in a range of colours. They work with your existing microscope setup.